Spero Ventures logo
Spero Ventures logo
Spero Ventures
spero.vc
spero.vc • HQ: San Francisco, United States • 11-50 employees • Founded 2018
HQ: San Francisco, United States • 11-50 employees • Founded 2018
Actively hiring
Venture Capital
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Spero Ventures portfolio

Spero Ventures (Venture capital) is known to hold 30 companies, 22 of them startups. 8 of them are hiring now, with 44 open roles. Its companies closed 3 venture rounds in 12 months, raising $50.6M. Most of them work in Hospitals & Health Systems, Conversational AI, Energy Storage.

Source: Alion Venture capital Oct 12, 2026
Investments
30
22 of them startups
Hiring now
8
44 open roles
Rounds in 12 months
3
$50.6M raised

Companies Spero Ventures has invested in

All 30 Hiring now 8
Tiny Health Microbiome Series B $33M · this month 14 roles portfolio pageSep 25
Sora Fuel Generative Video · United States Venture round $14.6M · 6 mo ago portfolio pageSep 25
Mobius Materials Marketplaces · United States Venture round $3M · 9 mo ago portfolio pageSep 25
Remark Retail & Commerce AI Series A $16M · 15 mo ago portfolio pageSep 25
Persist Conversational AI · United States Series A $12M · 16 mo ago portfolio pageSep 25
Corvus Robotics Logistics & Warehouse Robotics · United States Venture round $7.5M · 2 yr ago 7 roles portfolio pageSep 25
Base Operations Threat Intelligence · United States Venture round $14.1M · 2 yr ago 1 role portfolio pageSep 25
Oova Diagnostic Tests & IVD Venture round $10.3M · 3 yr ago portfolio pageSep 25
Wattch logo Energy Storage · United States Venture round $3.5M · 3 yr ago portfolio pageSep 25
Clarity Sensors & Transducers Venture round $6.7M · 4 yr ago portfolio pageSep 25
Singularity Energy United States Venture round $4.5M · 4 yr ago portfolio pageSep 25
Gencove logo Genomics & Genetic Testing Venture round $9.8M · 4 yr ago portfolio pageSep 25
Huckleberry Digital Mental Health Venture round $18M · 6 yr ago 2 roles portfolio pageSep 25
Canopy Works Hospitals & Health Systems · United States 13 roles portfolio pageSep 25
Hyro Contact Center Software 2 roles portfolio pageSep 25
Mast Reforestation Environmental Science · United States 2 roles portfolio pageSep 25
Euclid Power Solar Energy · United States 1 role portfolio pageSep 25
Allie AI Machine Learning portfolio pageSep 25
Aralez Bio United States portfolio pageSep 25
Confirm portfolio pageSep 25
Eli Operating Systems portfolio pageSep 25
Guide United States portfolio pageSep 25
Juno logo portfolio pageSep 25
Marc Tarpenning portfolio pageSep 25
Pickaxe AI Agents portfolio pageSep 25
TalkShopLive portfolio pageSep 25
TELO Trucks portfolio pageSep 25
VistaPath Biosystems Hospitals & Health Systems portfolio pageSep 25
With Leaf portfolio pageSep 25
👋, I'm Andrew! portfolio pageSep 25

Focus

Markets
Hospitals & Health Systems7%
Conversational AI7%
Energy Storage7%
Environmental Science7%
Alternative Fuels3%
Generative Video3%
AI Agents3%
Machine Learning3%
Where its companies are
United States40%
Stage of its companies
Venture, series not stated77%
Series A15%
Series B8%

Questions about Spero Ventures

How many companies has Spero Ventures invested in?

Spero Ventures is known to hold 30 companies: 22 startups, and 0 exits so far, read from its own portfolio page and the funding rounds that name it.

Is Spero Ventures investing now?

Spero Ventures has no round in the press in 12 months and no new company on its portfolio page in 90 days.

What does Spero Ventures invest in?

The markets of the companies Spero Ventures holds: Hospitals & Health Systems (7%), Conversational AI (7%), Energy Storage (7%), Environmental Science (7%), Alternative Fuels (3%).

Which Spero Ventures portfolio companies are hiring?

8 companies Spero Ventures holds are hiring now, with 44 open roles listed on this page.

Who does Spero Ventures invest alongside?

The investors that hold the most companies together with Spero Ventures: Y Combinator, Scribble Ventures, Techstars, Mindset Ventures, Good Growth Capital.

How this page is made

A company counts as a holding when the investor’s own portfolio page links to it, a program’s catalog lists it, or a funding round in the press names the investor. The numbers are rebuilt every night; each company shows where it came from and when it was first seen.

Sources: its portfolio page, read Oct 3

Spero Ventures portfolio: 30 known companies. Alion, Oct 12, 2026. https://alion.io/company/spero-ventures/portfolio

Licence: CC BY-SA 4.0JSON