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Salary
$148k – $193k per year
Location
Remote (United States)
Seniority
Senior · 7+ years exp
Visa
H-1B filings in 12 months: 30
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 30, 2026. First seen by Alion on Aug 18, 2026. BeOne Medicines scores B on the Alion truth index.

Overview
Company
Impact
Profile match
BeOne Medicines, formerly BeiGene, is a global oncology company that discovers, develops, manufactures and sells cancer medicines, including the BTK inhibitor Brukinsa and the PD-1 antibody Tevimbra for hematologic malignancies and solid tumors. Founded in 2010 in Beijing, it runs research, clinical development and manufacturing across China, the United States and Europe, with major sites in Hopewell, New Jersey, San Carlos, California and Warsaw. Its US business is run from Cambridge, Massachusetts. The company is headquartered in Basel, Switzerland.

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

General Description:

The Global Commercial and Medical Affairs Technology team at BeOne is seeking a Senior Manager, AI implementation to help operationalize AI capabilities across Commercial and Medical teams. This role sits at the intersection of oncology data, customer and patient journey data, GenAI implementation, and enterprise data platforms.

This role will help define the semantic layer over BeOne's commercial and medical data warehouse, ensuring structured and unstructured data assets are described consistently so AI models, RAG experiences, insight engines, and BI layers can leverage the right data with the right context.

The Senior Manager will coordinate with Commercial, Medical, Data Engineering, Data Science, Compliance, Privacy, and field teams to ensure free-text insight collection, RAG chat interfaces, AI-generated outputs, and customer journey solutions are implemented with appropriate guardrails, traceability, and business relevance.

The ideal candidate brings 3-5 years of recent oncology experience focused on patient journeys and patient-level data, strong familiarity with commercial and medical data ecosystems, and a hands-on builder mindset with the ability to write code, explore emerging platforms, and turn AI concepts into practical capabilities that make cross-functional workstreams more efficient.

Key Responsibilities:

Semantic Layer, Data Context & Insight Engine

  • Lead creation and ongoing governance of a semantic layer on top of the commercial and medical data warehouse, including entities, attributes, definitions, metrics, business rules, relationships, lineage, and data quality expectations.
  • Partner with data engineering, BI, MDM, and business stakeholders to define how patient, HCP, account, field insight, engagement, journey, patient-level, and medical/commercial data assets should be represented for AI use.
  • Translate data definitions and business context into reusable metadata, ontologies, knowledge objects, and retrieval patterns that improve AI model grounding.
  • Support the design of an insight generation engine on top of the data and semantic layers, ensuring outputs are accurate, explainable, timely, and available through the appropriate BI and workflow layers.
  • Define evaluation criteria for data readiness, retrieval quality, insight accuracy, confidence, freshness, source attribution, and business actionability.

Commercial & Medical AI Guardrails

  • Coordinate across Commercial, Medical, field, compliance, privacy, legal, and technology teams to ensure AI guardrails for free-text inputs and field-collected insights are implemented correctly.
  • Establish practical operating procedures for acceptable use, input validation, sensitive data handling, prompt and response controls, human review, and exception management.
  • Monitor adoption and quality of field insight capture workflows, identifying risks related to incomplete context, inconsistent terminology, duplication, bias, hallucination, or inappropriate data use.
  • Ensure AI outputs appropriately reflect approved data sources, business rules, medical/legal/regulatory considerations, and commercial/medical operating boundaries.

RAG, Chat & Knowledge Retrieval Solutions

  • Validate and continuously improve RAG-based chat interfaces across Commercial and Medical teams, including source coverage, retrieval performance, answer quality, citation/traceability, feedback loops, and escalation paths.
  • Work with teams to ensure data and unstructured knowledge assets are collected, curated, permissions-aware, and available for use in chat, summarization, insight, and assistant experiences.
  • Partner with data science and engineering teams to refine embeddings, chunking strategies, metadata filters, prompt templates, evaluation datasets, and LLMOps/monitoring capabilities.
  • Design and run testing processes to confirm RAG outputs are accurate, grounded, consistent, and fit for use in business and medical workflows.

AI-Generated Meeting-Ready Outputs

  • Enhance existing RAG and GenAI models to generate meeting-ready decks, briefs, summaries, talking points, and insight narratives based on unstructured commercial and medical content.
  • Define reusable templates and quality checks for AI-generated presentation materials, including audience, purpose, key message, evidence, caveats, next-best-action, and source attribution.
  • Partner with field, brand, medical, and other commercial teams to connect unstructured content with structured data and BI outputs so meeting materials are timely and decision ready.
  • Drive adoption of automation that reduces manual preparation time while maintaining quality, compliance, and stakeholder trust.

End-to-End Customer Journey & BI Integration

  • Ensure end-to-end customer and patient journey solutions leverage AI capabilities in the intended manner, grounded in BeOne's data landscape and aligned to priority use cases.
  • Map AI use cases to upstream data sources, semantic definitions, model workflows, BI outputs, CRM/field workflows, and user actions.
  • Partner with Commercial and Medical teams to validate that AI-generated insights are reflected accurately and timely in dashboards, reporting layers, and performance-management routines.
  • Bring oncology patient journey expertise to ensure AI-driven insights are clinically and commercially meaningful, with appropriate granularity and limitations clearly understood.

Hands-on Prototyping & Enterprise Implementation

  • Write code and build prototypes, scripts, prompts, evaluation harnesses, APIs, or workflow automations to test and accelerate new AI capabilities.
  • Explore emerging AI platforms, data products, and vendor capabilities; recommend practical fit-for-purpose solutions and help transition successful experiments into scalable delivery.
  • Engage with Corporate Affairs, Procurement, Clinical, and other enterprise teams to identify and support AI solutions that improve efficiency in high-value tasks.
  • Produce documentation, training, demos, and user guidance that help teams adopt AI responsibly and effectively.
  • Support roadmap planning, backlog prioritization, vendor coordination, delivery milestones, and measurement of value/impact.

Governance, Security & Compliance

  • Apply AI governance, model validation/evaluation, data privacy, information security, and regulatory expectations, including HIPAA, GDPR, GxP where applicable.
  • Document model assumptions, source data, prompts, retrieval configurations, known limitations, review controls, and audit trails.
  • Partner with compliance, legal, privacy, and security teams to ensure patient-level data handling, role-based access controls, and promotional/medical content boundaries are respected.
  • Implement monitoring and feedback mechanisms for accuracy, data quality, fairness, hallucination risk, user experience, and operational performance.

Education Required:

  • Bachelor's degree in AI, Data Science, Computer Science, Engineering, Statistics, Biomedical Informatics, Life Sciences, or a related quantitative/technical field; Master's degree preferred.

Qualifications:

Technical & Domain Expertise

  • BS Degree with 7+ years of experience across data products, AI/ML, GenAI implementation, data engineering, BI, or commercial/medical technology in enterprise environments.
  • 3+ years of recent oncology experience focused on patient journeys, patient-level data, customer/HCP engagement, commercial domain, medical domain, and related domain knowledge.
  • Strong understanding of pharmaceutical/biotech commercial and medical data ecosystems, including patient journey data, field insights, CRM/field activity, medical/commercial knowledge assets, omnichannel engagement, and BI/reporting layers.
  • Experience building or governing semantic layers, data catalogs, business glossaries, metadata frameworks, ontologies, knowledge graphs, or metrics layers for AI use.
  • Hands-on experience with GenAI/RAG concepts, including document ingestion, embeddings, vector databases, retrieval strategies, prompt engineering, grounding, evaluation, monitoring, and guardrails.
  • Coding proficiency in Python and SQL; ability to prototype independently and partner effectively with engineering teams.
  • Experience with data warehouse, lakehouse, and cloud platforms such as Snowflake, Databricks, AWS, Azure, or GCP; experience with BI tools such as Power BI, Tableau, Qlik, or similar preferred.
  • Familiarity with LLMOps/MLOps, APIs, workflow automation, data pipelines, and unstructured data processing.
  • Understanding of data privacy, security, compliance, and responsible AI practices in healthcare/life sciences environments.

Business Acumen & Leadership

  • Ability to translate ambiguous business needs into practical AI/data products and technical requirements.
  • Strong cross-functional collaboration with Commercial, Medical, field teams, data science, engineering, BI, compliance, privacy, legal, procurement, corporate affairs, clinical, and vendor partners.
  • Executive-ready communication and storytelling skills; ability to explain AI outputs, data limitations, and recommended actions to technical and non-technical audiences.
  • Demonstrated ability to drive adoption, standardization, and change management across matrixed teams.
  • Builder mindset; comfortable testing new tools, writing code, learning quickly, and moving from proof-of-concept to scalable capability.
  • Strong project/product management skills, including prioritization, requirements definition, delivery coordination, and value measurement.

Nice to Have

  • Advanced degree in AI, data science, biomedical informatics, life sciences, computer science, statistics, engineering, or related field.
  • Experience with oncology product launch, patient-level claims/EHR/EMR data, data tokenization/identity resolution, MDM, or customer 360 capabilities.
  • Experience with automated deck generation, document intelligence, copilot/assistant experiences, or agentic workflows.
  • Experience designing AI evaluation frameworks, prompt libraries, guardrail testing, and monitoring dashboards.
  • Experience in commercial and medical data governance or AI governance committees.

Travel

  • Estimated 10-15%, primarily for key planning sessions, workshops, stakeholder reviews, or major launch initiatives.

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

  • Fosters Teamwork
  • Provides and Solicits Honest and Actionable Feedback
  • Self-Awareness
  • Acts Inclusively
  • Demonstrates Initiative
  • Entrepreneurial Mindset
  • Continuous Learning
  • Embraces Change
  • Results-Oriented
  • Analytical Thinking/Data Analysis
  • Financial Excellence
  • Communicates with Clarity
Salary Range: $147,800.00 - $192,800.00 annually

BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact [email protected].

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